The ins and outs of clinical drug development can be confusing and complicated. It is a system designed to be thorough and meticulous to ensure that adequate levels of safety and research ethics are complied with throughout the process. Most Americans (over 95% according to one study) never participate in clinical drug development studies, yet the value of such medical research studies is significant. Just over 45% of those surveyed indicated that they somewhat agreed with the statement: Participating in clinical trials is as important to the health care system as donating blood. So how do clinical trials work?